Consequently, Crypton took a different direction with their updates in comparison to the Appends of Hatsune Miku, Kagamine Rin & Len, and Megurine Luka. Wat described how different the intention of the CV series was to the concept of KAITO and MEIKO during the development of KAITO V3. Spurred on by the items held by Hatsune Miku and KAITO, it became popular to feature MEIKO with One Cup Ozeki (sake).
In Maker Hikoushiki Hatsune Mix she is usually portrayed as a middle-aged woman, however KEI mentioned in a magazine interview that what he depicts in the comic is not official. The name originates from the eponymous derivative character, depicted as herself in her younger days. She is often misnamed Sakine Meiko by fans. 'Megumi' was also a name considered during her development. MEIKO's codename was 'HANAKO' it likely came from 'Hanako Yamada (山田花子)', a placeholder name for female characters, and the Japanese equivalent to 'Jane Smith'. 'MEIKO' comes directly from her voice provider's name, 'Meiko Haigō.