They have formulas that look for patterns in the X and Y co-ords. It can't detect movement but it WILL pick up clicks. If you fail every random event or if you log out every time you get a random event, you're likely to be banned. If you never say anything in the game or if you don't respond to players who talk to you, it'll increase the chances you'll be banned. If behaves as though you never get bored and never sleep, you may get permanently banned with no warning. If you click on an exact color or two with 100% accuracy, they may be able to detect that. If your clicks hit an exact pixel location repeatedly, or if your mouse moves in a perfectly straight line between clicks, or if you delay a particular number of milliseconds between clicks you may get permanently banned with no warning. What it CAN do, I think, is analyze the movements of your mouse while it is on the runescape screen. As far as I know, Runescape DOES NOT have the ability to check what processes are running, what's on your screen, or what you do with your computer outside of the Runescape screen.
